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A total of 82 locations significant at least at the 5% chromosome-wise threshold were detected.
These consist of a channel estimator and a linear filter (for the estimation of the transmitted symbols), interconnected by a feedback loop through a symbol-wise threshold detector.
In Niblack's method [23], a pixel-wise threshold is calculated based on the standard deviation and the local mean of all pixels in the moving window over the gray image.
CFAR algorithms detect targets by pixel-wise threshold operation, in which the threshold is adaptively computed for each pixel according to the statistical property of pixels within a local window [1 7].
Significant epistasis was identified in Spain 2 at a P<0.05 genome-wise threshold set by 500 permutations.
We next tested all possible marker and 1 cM marker interval pairs for interactions with experiment-wise threshold of P = 0.05 by 500 permutations [28].
For all group analyses, we applied a voxel-wise threshold of p<0.05 (family wise error corrected) and a minimum cluster size of 10 coherent voxels.
As before, a one-sample t-test was used (23 degrees of freedom) and a voxel-wise threshold of p<0.001 (uncorrected; T>3.48) was used to generate the cluster images.
This value is slightly lower than that of the F2 population (Fig 3C), but exceeds the family effect level of 1.35 and the 90% experiment-wise threshold level of 2.29.
This exceeds the threshold levels obtained by calculating family residual effects, which were 1.19 and 1.39, and the 95% experiment-wise threshold level of 2.79 and 2.60 in G8 and G10 data sets, respectively, as generated by permutations.
All analyses were corrected on a voxel-wise threshold of P < 0.001.
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