Increasing the percentage ASiR resulted in a step-wise reduction in mean objective noise (p < 0.001 for all comparisons).
Exposure of strain TMB3500 to step-wise reduction in pH from 5 to 3.7 over 3600 h in a chemostat led to successful growth and ethanol production in the presence of inhibitory concentrations of acetic acid, furfural, HMF and vanillin over the whole pH range.
The step-wise reduction in activity observed with the shorter deletion constructs in the HEK 293 cells suggests the presence of multiple regulatory elements, each of moderate activity (Figure 2D).
Increasing PTT resulted in a step-wise reduction in the rate of 3-month confirmed (Fig. 2A) and 12-month sustained (Fig. 2B) worsening events.
Thus, in cohort step C, two out of six patients reached the stopping rule of step-wise reduction in saline hydration in the first two treatment cycles.
These studies necessarily begin in highly supervised hospital settings and progress through early feasibility, transitional, and, finally, pivotal trials, each with step-wise reduction in monitoring requirements as system performance and functionality are established under normal and stress conditions.
GUS activity was present throughout the whole plant in five-week-old plants, and showed a step-wise reduction in both expression area and level in three-week-old and four-week-old plants.
When ICP was controlled (<20 mmHg for 48 hours), we conducted a step-wise reduction in the barbiturate coma in steps that reduced the dosage by 50% every 24 hours until the infusion was suspended.
A large Italian registry comprising >250,000 acute hyperglycaemic complications reported annual trends and a step-wise reduction in hospitalisation for diabetic complications, but did not provide specific data for DKA [ 3].
In this protocol, all patients were placed on pressure-support ventilation at a level to maintain a spontaneous respiratory rate of 20 28/min and involved a step-wise reduction in the level of pressure support.
