Thus, while areas of the ToM and gaze perception networks in the control and ASC groups did not differ in their overall response to direct and averted gazes (no main effect of group in the above analysis of voxel wise effects), the connectivity between the components of this network is significantly reduced in ASC during a sequence of direct and averted gaze trials.
Pair-wise effect sizes between drugs, probabilities of being the best drug and ranking of drugs were modified.
Estimated drug effects relative to the placebo from both adjustment models were corrected (i.e., similar to those from NMA of FDA data) for some drugs but not others, which resulted in differences in pair-wise effect sizes between drugs and ranking.
The median relative difference, in absolute value, between pair-wise effect sizes from the regression model and the standard NMA model was 57.3% (25%75%75% percentile 30.3% – 97.6%); the median relative difference between the selection model and the standard NMA model was 29.2% (15.1% – 46.1%).
Along the line of the regression-based approach of Moreno et al. in conventional MA, the authors introduced a measure of study size as a regression variable within the NMA model and identified a mean bias in pair-wise effect sizes.
When MAF equals 0.5, nearly all the methods designed to detect pair-wise epistasis could effectively detect Models 1 3 in various marginal pair-wise effects with no LD effects.
These ROIs were defined from contrasts/voxel-wise effects from Experiment 1, and sampled from the independent Experiment 2. RSA70 from the event-related data was computed as using CoSMoMVPA, an toolbox in MATLAB (MathWorks, Natick, MA 74.
To accommodate the setting of PLINK, BOOST, EDCF, and SIXPAC on pair-wise effects detection only, we decomposed the high-order effects to multiple pair-wise effects, e.g., detecting the complete set of all three pair-wise relations AB, AC, and BC, which is counted as detecting the three-order relationship ABC successfully.
Monostable switches may be realized in different ways, for instance through co-operative effects of regulating enzymes and combination of stage-wise effects such as in MAP Kinase cascades.
Group-wise effects on Ki-67 staining intensity for genes in the two proliferation modules were analyzed per module by comparing the mean module Ki-67 intensity to a random intensity distribution based on 10,000 sampled gene groups of the same size as the assayed module.
