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Patients with greater than mild pulmonic stenosis, residual ventricular septal defect or poor echocardiographic windows were excluded.
Three patients, who had surgical dressings over the chest/abdomen precluding satisfactory transthoracic echocardiographic windows, were excluded.
By knowing the biologically functional genomic windows of these motifs a priori, motifs that did not occur in biologically functional genomic windows were excluded, partly correcting for spurious matches.
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The EEG data during rest was visually inspected for artifacts (e.g., epileptiform spikes), and periods from 2 s before to 2 s after each artifact window were excluded from further analyses.
Pregnant patients and patients with poor echo window were excluded.
Patients for whom the TCD examination was not possible, due to absent or suboptimal temporal insonation window, were excluded.
Patients with insufficient temporal window were excluded from the study.
Pairs containing more than 25 putatively nonparalogous sites in a window were excluded from further analyses.
Subjects with a diagnosis of depression prior to the five-year window were excluded.
54 Patients in whom a TCS of the SN was not possible because of a non-accessible bone window were excluded from the study resulting eventually in a group of 196 patients.
For cancers with sufficient case numbers, we performed a fifteen-year latency analysis by restricting inclusion to the residences occupied by participants at least fifteen years prior to the diagnosis or index year (Residences within the fifteen year window were excluded because geographical location within that window was assumed not relevant to the outcome).
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