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Subsequent to retrospective validation, multimarker models are developed, either as part of phase Ic, with the initial cohort of patients, or as part of phase II, in a retrospective study using patients different from those of phase I. Whether initially developed in phase I or II, this model will always undergo refinement with the second group of patients.
First, the items and domains of MORE will undergo further refinement using cognitive debriefing interviews with a wide range of international stakeholders.
First, we anticipate that the vervet genome assembly will undergo further refinement; as a result, we will obtain a more complete delineation of vervet structural genomic variation and also close current gaps in SNP coverage.
Topics undergo refinement to ensure relevant questions of appropriate scope and useful reviews.
If a region does not meet the LRR requirements, it will undergo BAF-based CUSUM boundary refinement if the BAF median meets the BAF threshold requirements (|median| > 0.1 + the local baseline mBAF median).
Complex research studies often undergo refinements in their early stages.
Carter will undergo further testing.
Instead he will undergo surgery.
Willis will undergo further evaluation.
He will undergo radiation treatment in July.
The United States will undergo a similar process.
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