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Until such a signature is identified and validated, it will remain difficult to implement correction strategies for individual patients.
Nevertheless, approaches to control the global spread of resistance will remain difficult to implement and will require intensive surveillance and screening efforts.
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While fish-based freshwater bioassessments are cost-effective and perform well in speciose systems, such bioassessments remain difficult to implement in species-poor Mediterranean regions.
Therefore patient strategies that can potentially reduce the morbidity, as seen in our patient, remain difficult to implement.
As a result, uniform therapeutic strategies remain difficult to implement, and some stage 4s cases may receive unnecessary cytotoxic therapy.
Even with the new system, it will remain difficult to order obscure options on popular models.
The ratio at larviposition is equally unknown, and will remain difficult to assess.
However, small, rare and dynamic complexes will remain difficult to deal with.
However, study results will remain difficult to interpret while the targets of mitochondrial therapy are not clearly defined.
Investigations addressing SAD will remain difficult due to the problem of correctly identifying and quantifying this entity.
So it will remain difficult for them to raise money to up sticks.
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