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The mechanisms underlying these individual differences in vulnerability remain difficult to identify.
Novel disease genes remain difficult to identify in most genetic diseases, and in particular, in highly polygenic disorders.
Until such a signature is identified and validated, it will remain difficult to implement correction strategies for individual patients.
Even with the new system, it will remain difficult to order obscure options on popular models.
These questions will remain difficult to answer for as long as Martin declines to speak on the matter.
The ratio at larviposition is equally unknown, and will remain difficult to assess.
However, small, rare and dynamic complexes will remain difficult to deal with.
However, study results will remain difficult to interpret while the targets of mitochondrial therapy are not clearly defined.
Nevertheless, approaches to control the global spread of resistance will remain difficult to implement and will require intensive surveillance and screening efforts.
As a result, transcripts with low to moderate expression levels will remain difficult to quantify with good precision using current RNA-Seq protocols even at higher read depths.
So it will remain difficult for them to raise money to up sticks.
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