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Biomarkers that accurately identify individuals at risk for BC will improve efficacy of chemoprevention and early detection clinical trials.
We hypothesize that new therapies that can efficiently attract tumour-suppressive immune cells to the tumour area will improve efficacy of current cancer therapies.
Whether increasing the dose of primaquine from 45 mg to 60 mg will improve efficacy needs to be addressed in future studies.
This will help determine optimal biological dosing, preventing toxicity to normal cells and will improve efficacy of HSP90 inhibitors in various tumour types.
CTC analysis has the unique potential to offer a minimally invasive 'liquid biopsy' sample, easily obtainable at multiple time points during disease history, thus providing valuable information on the very early assessment of treatment efficacy and helping towards establishing individualised treatment approaches that will improve efficacy with less cost and side effects for BC patients.
Given the efficacy of pemetrexed in combination with cisplatin as a first-line doublet and as a maintenance agent (when not used in the induction regimen), we designed a phase III study to determine if pemetrexed maintenance therapy will improve efficacy over placebo following cisplatin/pemetrexed induction therapy in patients with advanced nonsquamous NSCLC.
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Individual therapy focusing on certain gene mutations will further improve efficacy.
Emerging data suggest that the addition of targeted biological agents to such regimens will further improve efficacy.
Implementing these findings in clinical gene therapy protocols will improve the efficacy, safety, and sustainability of gene therapy and generate new opportunities in the field of gene editing.
This will improve pesticide efficacy and decrease the required spraying frequency.
MLA will improve the efficacy of this type of continuous release strategy.
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