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Ultimately, RCTs will help to delineate clinical indications in these 2 main settings (COPD and ARDS).
For example, targeting PACAP receptor sub-types and using inducible animal models to rule out compensatory mechanisms will help to delineate the role PACAP plays in CSD.
Future studies will help to delineate these degradative QC pathways further.
Understanding the precise level at which ErbB2 up-regulates survivin expression will help to delineate the underlying signal transduction pathways and will allow better targeting of survivin in ErbB2-overexpressing breast cancer cells.
Further studies will help to delineate the mechanism by which SEC13 and GNL2 activate NMD in human cells, as well as their involvement in the described alternative NMD branches [ 36– 36].
This approach highlights the exquisite cell/tissue-specific actions of the ERα subfunctions and will help to delineate the spectrum of action of selective ER modulators, as that of the selective ERαAF1 activator tamoxifen used in the present study.
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Further knowledge of the innate immune response in the CNS will greatly help to delineate the novel therapeutic routes to protect from CNS inflammation and neurodegeneration.
Analysis of membrane phospholipids in L. hongkongensis will reveal the types of unsaturated fatty acids that it possesses and help to delineate the possible biosynthetic pathway.
Further analysis using different restriction enzymes and additional probes may help to delineate the genomic structure of the region but will still be challenging due to the presence of LCRs.
The verdict may help to delineate a new relationship between active and former players — positively or otherwise.
Systematic investigations with routinely available tests can help to delineate mechanisms of thrombocytopenia [218, 232, 234].
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