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The assigned detection number measures the risk that the failure will escape detection.
A high detection number indicates that the chances are high that the failure will escape detection or, in other words, that the chances of detection are low.
He reinforces this claim by arguing that it is impossible for someone who violates the compact to be confident that he will escape detection (XXXIV-V).
Finally, we have found that highly divergent variants will escape detection because of inefficient extension from the consensus oligonucleotides on the array.
In addition, during the early stages of the epidemic a high R in the source region acts to increase the probability that an infected traveler has been infected quite recently and hence will escape detection due to being asymptomatic during their travels (Figure 2A).
After the digestion with marking enzymes, cDNA sequences that remain on the column and that lack recognition sites for any releasing enzyme will escape detection.
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The reduction of the length of the immobilized cDNA fragments generated by marking enzymes applied concomitantly increases the chance that a fragment will not be cleaved by any releasing enzyme and will therefore escape detection.
If rare variants in a population are present at levels below 0.3%, they will likely escape detection, yet this may include variants that could affect population dynamics.
2) The assay depends upon having completely methylated or unmethylated DNA at the relevant restriction sites within a given Csp6I fragment: If a fragment shows partial methylation on either the silent or active allele, the signal for that allele will probably escape detection.
Conversely, the pathogen will counter-evolve to escape detection, again placing selective pressure on the host population for new mutations that improve the immunity protein.
Due to the deleterious effects of mismatches there is a need for a system that will correct the errors that escape detection by the proofreading activity of DNA Polymerases.
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CEO of Professional Science Editing for Scientists @ prosciediting.com