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If the free enzyme fractions of Pyk and Ppc are too low, much of the PEP concentration will be trapped in complex with the enzyme, and the PEP pool will become limiting.
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Subsequently, the realm of choices will become limited.
Between 1°C and 2°C increases in global mean temperatures most species, ecosystems and landscapes will be impacted and adaptive capacity will become limited.
While prosecutors can interrogate Ghosn daily at Tokyo detention centre, Ghosn's time to work on his defence with his lawyers will become limited.
With increasing burdens on its spending, the ability of governments to support consumer spending – as they have done in recent years with a constant diet of tax credits and tax cuts – will become limited.
This, he thinks, is not only diminishing for them, but for music, which will become limited to a select elite of passionate aficionados "away from the rest of the world, away from the human problems.
Since a lightpath may travel a long distance, for high bit rates, the effect of the physical impairments along a lightpath may become very significant (leading to high bit-error rate (BER)); and the signal's maximum transmission range, which depends on the bit rate, will become limited.
Since fossil sources for fuel and platform chemicals will become limited in the near future, it is important to develop new concepts for energy supply and production of basic reagents for chemical industry.
It is not only that fossil carbon sources will become limited in the future, but there is also a growing pressure to renounce the exploitation of currently treated and prospected sites for environmental reasons.
Without developers, Oracle's cloud play will become limited to a traditional base of customers who have a heavy dependence on legacy solutions and are committed to integrating Oracle-engineered systems.
If the results demonstrate no benefit, then PAC use will become limited to rescue therapy in a small number of select patients.
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CEO of Professional Science Editing for Scientists @ prosciediting.com