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Given the large number of candidate intervals identified from the whole-genome scan studies, and the potential large number of genes within those intervals, the next step towards underlying gene identification will be refinement of the mapped intervals.
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Admittedly many of these will be refinements and unnecessary for some rudimentary form of phagocytosis.
"There will necessarily be refinements as the concepts are developed," Mr. Rubenstein said.
Within the scope of this paper, the focus will be on refinements of the Attitude system.
As new data emerge, integration of novel biomarkers into the consensus definition will be a welcome refinement.
Conclusions: These EST-SSR markers for pea will be useful for refinement of pea linkage maps, and will likely be useful for comparative mapping of pea and as tools for marker-based pea breeding.
While further method development will be needed for refinement of cross-flow rates, solvents and sample preparation, its first application to colloidal silver preparations measured concentrations generally falling significantly short of labeled contents.
While the overall net improvement in performance is perhaps the most relevant endpoint, especially in relation to patient safety, identifying the contribution of EHR skill acquisition vs. improved cognition will be essential for refinement of the activity.
Although generic concepts of protein misfolding and fibril formation have been established, the major challenge for future studies will be in the refinement and improvement of these models, so that the shape of the folding and aggregation landscapes can be predicted under conditions relevant to the living cell.
An important challenge for the future action of UNICEF will be the adjustment, refinement and prioritization of goals and strategies within the framework of the Convention on the Rights of the Child, thus making explicit choices in favour of child-cantered approaches.
We may expect that further criteria of adequacy for subjective probabilities will be developed — perhaps refinements of 'scoring rules' (Winkler 1996), and more generally, candidates for playing a role for subjective probability analogous to the role that truth plays for belief.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com