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Eligible children will be followed using Post-Concussion Symptom Inventory, a validated tool in children as young as 5 years.
A predefined statistical analysis plan will be followed, using SAS software V.9.3 (Cary, North Carolina, USA), with the intent-to-treat approach.
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Non-responders will be followed up using our standardised CTU follow-up procedures for trials.
Health events will be followed up using a declaration by participants on the website and, after collection of medical records, it will be validated by independent committees of experts.
Any individuals whose data has not been received fourteen days after the instruments were posted to them will be followed up using a standardised operating protocol: reminder letter, then telephone call, and then contact with nominated secondary point of contact if none of the previous modalities of contact have been successful in reaching the individual or their voicemail.
If significant between-groups differences are found, each will be followed up using two a priori linear contrasts: the first comparing the control group with all the unilateral CP participants and the second comparing the left are right unilateral CP participants.
The CONSORT statement will be followed and used for reporting results.
The group will be followed up prospectively using neurocognitive testing between the ages of 6 and 10 years.
Independently of inclusion criteria, the health-related quality of life will be followed over time using the instrument EQ-5D [ 19] as well as the clinical parameters triglycerides, HDL and LDL.
The participating children will be followed through the use of questionnaires and health examinations at 1 month, 6 months, 1 year, 3 years, 6 years, and 12 years of age.
This study will be followed by more work concentrated on using different neural network-based control algorithms for the control of extraction contactors.
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