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Demographic and clinical data will be collected of each patient.
Prior to the examination, baseline data will be collected of each participant.
Samples will be collected of whole blood into 10 ml EDTA vacutainers, maintained at ambient temperature and transported overnight to a centralized biobank named REDinREN (Spanish Renal Research Network).
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Information will be collected on method of determination of reference standard, execution and blinding.
Data will be collected on number of different outcomes using a range of methods.
Extra blood samples of serum DHEA and AMH concentrations will be collected on the day of egg collection.
One-year follow-up measurements will be collected for most of the baseline procedures, with the exception of the lumbar puncture, the PET imaging, and apolipoprotein E genotyping.
In addition, cord blood will be collected for assessment of insulin, c-peptide and glucose levels.
76 Twenty-four hourineine samples will be collected for analysis of urinary creatinine, 3-methylhistidine (3-MH) and urea levels.
Stool samples will be collected for analysis of gut microbiota and for fecal water metabolomics using H-NMR.
Damschroder LJ, 2009 [ 43] Different types of data will be collected to explore facilitators of and barriers to DCM implementation, using the CFIR framework.
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