Transplantation of PSM cells from a zebrafish with continuously activated Notch to a wild-type embryo caused acceleration of her1 oscillations in adjacent cells and consequently an anterior shift of the segment positions [ 103].
In addition, transgenic tadpoles developed faster than wild type siblings, with an acceleration of as much as 7 days out of the 30-day experiment.
It also explained why acceleration data from wild cheetahs pursuing different prey showed different cornering behaviour with prey type.
The wild-type enzyme showed no acceleration for DECP hydrolysis over buffer at <20 μM enzyme, suggesting a kcat/ KM of ∼10 3 M–1 s–1.
This is the first investigation of continuous annual heart rhythms and associated body acceleration activities recorded from bears in the wild.
Furthermore, there was a greater pressure load in the pulmonary artery in ku70 −/− mice than in the wild-type mice, based on the shorter Doppler-determined acceleration time of blood flow through the pulmonary artery.
Evidence of mineralization of the kidney of wild-type mice was also noted when kept on an acceleration diet, but to a much lower extent than in homozygous and heterozygous asj mice (Fig. 1C; Fig. 3B).
The predictions of the model were compared with the pursuit strategies of wild cheetahs, which were studied using collars equipped with tags to measure acceleration as the predators chased prey of different sizes from hares to large antelopes called gemsboks.
Preliminary data in cell lines showed that downregulation of NOTCH1 in NOTCH1 mutant cell lines leads to a modest effect of cell cycle acceleration and anti- NOTCH1 agents are only effective in NOTCH1 wild type cell lines.
Fungal infection eventually led to an apparent acceleration of senescence in a density-dependent fashion in both wild type and mutant, but the amount of chlorosis was greater in the mutant.
