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These bundles span almost the entire width of the cortex.
Cortical thinning is a decrease in the width of the cortex along the area of the bone where the fixture is implanted.
High-resolution images (1 pixel = 0.74 μm) were obtained within these regions of interest, spanning the full width of the cortex.
To illustrate interlaminar differences in zif268 expression we plotted profiles of mean gray value changes across the width of the cortex for 1 representative calibrated section for each group of animals by ImageJ software v1.45s (Figs 1B, 2 and 3).
The mean width of the cortex (pia to SCWM) in our material with VPM injections was 1739 μm for columns in arc 1 3, 1782 μm for arc 2 and 3 columns, and 1840 μm for all columns (arc 1 6; n = 7; Fig. 5 C ).
In these sickle mice, renal ischemia following total renal artery occlusion for 15 min resulted in a significant increase in creatinine and blood urea nitrogen levels that was associated with diffuse acute tubular necrosis extending across the entire width of the cortex, with large segments of cortical necrosis [ 22].
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Increased blood pressure was also associated with a reduction of the minimal width of the kidney cortex, but not with a reduction in kidney length.
Altogether, these results demonstrated that Nkx2.1 is expressed in a subpopulation of cortical GABAergic cells in the whole width of the human cortex at midterm.
This column is defined as a virtual cylindrical volume of cortical tissue that spans the width of the entire cortex (on average 1840 μm).
However, there was a highly significant decrease in cell width for cells of the cortex and stele in Spcdc25 compared with WT.
However, consistent with the narrowing of cell width in the cortex and stele, the overall girth of the RAM was narrower (P < 0.01) in Spcdc25 (91.67 ± 1.90 μm) compared with WT (124 ± 3.70 μm).
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