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L = length, and W = width The mice were also weighed regularly.
Tumor volumes were measured (0.5 × length × width) in mice on a weekly basis.
Furthermore, data from IGF1 conditional gain and loss of function studies in mice employing osteoblast specific gene promoters, such as Col1a1 and Col1a2, respectively, suggest that IGF1 gain of function resulted in increase length of long bones and cortical width in mice while loss of function resulted in decrease bone formation and bone mass (Jiang et al. 2006).
Mouse width was equivalent to 35 pixels, which was the mean width taken from 1393 ellipses manually drawn over the female access.
An average of 19 strides were used to calculate the rear stance width for each mouse.
There was no effect of lubiprostone on crypt width in WT mice (Fig. 3A,C).
The tumours were measured with callipers twice weekly (length × width) and the mice weighed.
Analysis of the footprints indicated statistically significant decreases in both stride length and base width of YG8sR mice compared with Y47R and B6 controls, whether both male and female values were taken together or when male and female values were considered alone (supplementary material Fig. S6).
In agreement, gait analyses of 20-week-old mice demonstrated that the rear stance width of Sil1−/−; Dnajc3−/− mice were significantly different from the stance width of Sil1−/− mice, but similar to that of wild-type and Dnajc3−/− mice (Fig. 6A).
The cumulative distributions revealed no significant differences in spine width between ApoEr2 knockout mice and wild-type mice (Fig 4F-H).
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