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Exact(9)
Some of the most widespread selection designs, such as single selection, yield power gains only when both the marker and quantitative trait loci (QTL) are relatively rare in the population.
Many of the studies provided clear evidence of widespread selection into the programme [ 22- 29, 29, 31, 32].
Given such a functional significance, we expect statistically overrepresented OSCs in coding sequences as a result of a widespread selection.
However, inadequate soil nitrogen should be the most widespread selection pressure in operation for both subspecies, irrespective of their locations.
The genetic change in carbaryl tolerance in the control rather than in the carbaryl treatment suggests widespread selection for insecticide tolerance in the field associated with land use intensity and suggests that this evolution comes at a cost.
To our knowledge, this is the first systemic report that provides a direct evidence of widespread selection on gene expression governed by evolution of whole-organism traits in mammals.
Similar(50)
If the SNPs in the H and HR sites that have high derived allele frequency are largely clustered in a few genomic regions, then the larger-than-background fraction of high frequency derived alleles may be an artifact of regional (i.e. not widespread) positive selection or even selective sweep due to linkage.
The finding of widespread positive selection in Rubisco suggests that either selection still continues to improve performance of this ancient critically important enzyme, or that adaptive evolution in rbcL may reflect the fine-tuning of Rubisco to optimize its performance in various gaseous and thermal conditions [ 4].
Most notably, there appears to have been widespread purifying selection in regulatory genes and frequent diversifying selection in receptor genes throughout mammalian history.
This may be more of a concern with widespread purifying selection in the genome than for selective sweeps at a limited number of loci, as the latter would likely result in less overall bias.
In light of widespread positive selection in plant Rubisco, the distribution of the positively selected sites in the secondary structure of Rubisco could suggest which parts of the structure are more sensitive to the selective forces.
Related(20)
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sweeping selection
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widespread corruption
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