Sentence examples for widespread roles from inspiring English sources

The widespread roles of metal ions in health and disease range from the requirement for intake of essential trace elements to toxicity associated with metal overload.

The widespread roles of HDAC6 are manifested in impaired immune response, bone development, and glucocorticoid receptor translocation as well as abnormal emotional behaviors observed in HDAC6 knockout mice (Zhang et al., 2008; Fukada et al., 2012).

The spatial expression patterns of BmRas were also ubiquitous, indicating their widespread roles in B. mori.

The study of PUF proteins in diverse model organisms revealed widespread roles for these proteins in embryonic development, stem-cell maintenance and neurogenesis [10], [11].

Given the ubiquitous nature of YB-1, and its widespread roles in the regulation of global translation and stability of transcripts, it is likely that additional regulatory factors are involved in its specific actions with respect to TGF-β1 TGF-β1

The 3-phosphorylated phosphoinositide second messengers have widespread roles in cell signaling.

The bank was fined £290m by US and UK regulators two years ago for a "serious, widespread" role in trying to manipulate Libor rates.

Does osteocalcin play a widespread role in problems like low sperm count and low testosterone, or is it more peripheral?

The boss of Barclays, Bob Diamond, is under mounting pressure after the bank was hit with fines of £290m for its "serious, widespread" role in trying to manipulate the price of crucial interest rates that affect the cost of borrowing for millions of customers around the world.

Due to the widespread role of horizontal gene transfer, branches in these trees are inevitably connected through genetic exchange events.

Recently we discovered that DnaD has a global remodelling DNA activity suggesting a more widespread role in bacterial nucleoid architecture.