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"widespread resistance" is correct and usable in written English.
You can use it to describe any kind of organized opposition on a large scale, such as a political protest movement. For example, "The citizens of the city organized a widespread resistance to the mayor's controversial new policy."
Exact(47)
Initially, Constable's meteorological accuracy met with widespread resistance.
There is widespread resistance, too, within many Muslim countries.
That means refuges may not be enough to stop the evolution of widespread resistance.
Given that there is widespread resistance to such a change in Europe, Germany may need Britain's support.
There has been no widespread resistance to the vaccine in Indonesia.
We should, therefore, expect widespread resistance from the health-care industry to even the most elegant cost-containment solutions.
Similar(13)
It might seem that widespread antibiotic resistance would not be that much of a catastrophe.
Widespread passive resistance caught the world's imagination; the tanks, inevitably, triumphed.
The protests have rattled the Kremlin, which has not encountered widespread political resistance for a decade.
Bassem saw no easy way to break the torpor and ignite a more widespread popular resistance.
We need to work with everyone to ensure the apocalyptic scenario of widespread antimicrobial resistance does not become a reality.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com