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Upon exposure to agents that damage DNA, Saccharomyces cerevisiae undergo widespread reprogramming of gene expression.
Thus, widespread reprogramming of the transcriptome in the AtPAP2 OE plants corresponded with their fast-growing phenotypes.
AtPAP2 overexpression resulted in a widespread reprogramming of the transcriptome in the transgenic plants, which is characterized by changes in the carbon, nitrogen, potassium, and iron metabolism.
Similar widespread reprogramming of the transcriptome was also detected in response to genotypic differences among soybean cultivars, and even in response to different times of the day at which plants were harvested.
In light of this evidence, we discuss how widespread reprogramming of DNA methylation patterns in cancer could drive the relocation of PRCs on chromatin, and contribute to carcinogenesis through alterations in gene expression.
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The most represented function was "nucleotide binding", which suggests widespread and dynamic reprogramming of the fungal transcriptome required to sustain pathogenesis and counteract host defense responses.
In addition to confirming a central role for OCT4 and SOX2 in reprogramming by defined factors, our model also suggests that non-specific widespread amplification of transcriptional noise may aid reprogramming of somatic cells to a pluripotent state.
A similarly widespread transcriptional reprogramming occurs following depletion of glucose in cells growing on rich medium and the ensuing transition to growth on ethanol (Derisi et al. 1997; Young et al. 2003; Brauer et al. 2005).
Reprogramming of adult differentiated cells into induced pluripotent stem cells (iPSC) is accompanied by widespread changes in the DNAm landscape (57).
That reprogramming of the brain is the point of constraint-induced therapy.
Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo.
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