The lesion can be single and self-limiting or may be widespread, and recurrence can be seen in the course of the disease.
Patient 2 died of widespread intra-abdominal recurrence at 15 months postsurgery.
This is due to an aggressive natural history of EPSCC – a course characterised by rapid local progression, early, widespread metastases and recurrence after treatment [ 3].
The authors conclude that due to the inaccuracy of contrast-enhanced CT to assess complete tumour response, regular follow-up examination after treatment is mandatory to detect early recurrence before widespread progression[ 3 ].
In comparison to other adult solid tumors, sporadic hemangioblastomas have a relatively low somatic mutation rate, but one that is similar to other intracranial neoplasms with a tendency to local recurrence but not widespread dissemination, such as meningiomas (1.6/Mb) [ 26, 35] and craniopharyngiomas (0.9/Mb) [ 19].
Because recording sites are distributed spatially over a relatively large area, spanning multiple anatomical fields (Figure 2), these results show that modulation of response strength due to call recurrence statistics is a widespread phenomenon within the auditory forebrain.
Standardized protocols for imaging those at risk of recurrence are not yet widespread but are likely to become established with improved therapies and patient life expectancy.
PET/CT with radioactively labelled Choline derivatives has found widespread use for the diagnosis of PCa recurrence in patients with biochemical failure.
The significance of such burrow-bearing layers as a characteristic stratigraphic marker unit is demonstrated by high burrow abundance, consistent stratigraphic position, lack of stratigraphic recurrence at these sites, and widespread geographic extent.
Also, the chance of recurrence is decreasing by the widespread use of adjuvant therapy and there is no need for lifetime follow-up.
