Policy or practice impacts can be widespread or localized, and may benefit specific or general populations.
In diseases that are primarily disorders of the brain, specific substructures of the brain are either more vulnerable to accumulate misfolded proteotoxins, or in settings of widespread proteinopathy, specific substructures are more prone to degeneration.
Genetically engineered mice with inducible and reversible Sirt1 knockdown in widespread, podocyte-specific, or tubular-specific patterns were generated.
Trypanosoma lewisi, transmitted by rat fleas, is a widespread pathogen specific to rats with records of human infection cases.
This effort would deserve dedicated time during pre a post graduate programs of all Radiologists in order to widespread this specific knowledge in all its aspects in our Radiological Community world wide.
This high incidence is a consequence of widespread prostate specific antigen testing in primary care [ 55].
We find this lesion to be widespread, but specific to one C58 laboratory strain lineage.
DOI: http://dx.doi.org/10.7554/eLife.04094.015 10.7554/eLiFigure94.016 Figure 5 figure supplement 3. Hypermethylation at CGs with low predicted methylation is a widespread and specific mark of cancer.
Despite this widespread reduction, specific sequences remain methylated until the second wave of demethylation occurs around E11.5, including differentially methylated regions (DMRs) in imprinted loci, CGIs on the X chromosome, and germline-specific genes.
We have shown that, when fragmented, many of the CL clusters which contain C20 4, C22 5, and C22 6 acyls (m/ z 303, 329, and 327, respectively) display a widespread though specific distribution in the thalamic, hippocampal, and cortical regions.
