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Despite astronomy's widespread inclusion in curricula prior to the 20th century, educational research in astronomy is a relatively new endeavor.
Despite the widespread inclusion of research education within nursing courses, there remain a number of tensions about the purpose, content, and philosophy underpinning such programmes.
High magnification images revealed that GFPu levels were similar between GFPu and R6/2; GFPu mice in the CA1 region, despite widespread inclusion body formation in the R6/2 brain (Figure 4).
The widespread inclusion of anthracyclines in the adjuvant setting limits their use as first-line therapy in metastatic disease.
For example, expression of an exon-1 fragment of mutant htt specifically in forebrain produces widespread inclusion pathology, but the authors did not report evidence of weight loss or abbreviated lifespans (40).
The widespread inclusion of sunscreen agents in personal care and consumer products (Gonzalez et al. 2006; National Library of Medicine 2007; Rastogi 2002) increases the potential for human exposure to BP-3.
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The question remains on how widespread the inclusion criterion is.
Even though some mouse models expressing N-terminal truncated mutant HTT exhibit abnormal behavioral and neurological phenotypes, other transgenic lines present widespread intracellular inclusion formation without any functional neuronal deficits.
As generalization to a mixture after training to a single substance has, to my knowledge, not been studied in a systematic way in other animals, it is currently impossible to draw conclusions on how widespread the inclusion criterion is.
They are also characterized by the presence of widespread nuclear inclusions of mutant polyQ-Htt in brain neurons.
A key histopathological feature of all forms of AxD is the widespread deposition of inclusion bodies within astrocytes known as Rosenthal fibers, consisting of aggregated GFAP, the small stress proteins HSP27 and αB-crystallin (Tomokane et al., 1991; Head et al., 1993; Iwaki et al., 1993) and likely other unidentified proteins.
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