Sentence examples for widespread gene expression from inspiring English sources

Moreover, mcDNA-loaded micelleplexes penetrated into 3D multicellular spheroids and promoted widespread gene expression.

The second is AMN1 in which the D368V loss of function mutation in BY is responsible for widespread gene expression changes [20], [23].

Thus, the phenotypic benefits of leucine requirement and cellular dispersal in the laboratory apparently facilitated the emergence of widespread gene expression changes, which might otherwise be intolerable to the cell in the wild.

Our data show that CR induces widespread gene expression changes and acts through highly evolutionarily conserved pathways, from microorganisms to mammals, and that its life-extension effects might arise partly from a shift toward a gene expression profile more typical of females.

This restricts the use of these promoters as a tool for strong and widespread gene expression.

We uncover widespread gene expression shifts associated with acclimation after an acute heat stress.

The study, which was written up in Science and measured the activity of 45 genes, revealed widespread gene-expression differences between root and leaf tissue.

The molecular background behind breast cancer progression is not well understood, but is associated with the accumulation of genetic aberrations, leading to widespread gene-expression changes in breast tumor cells.

In these widespread cases, gene expression is mapped in an Eulerian specification, using spatial coordinates at a given time.

Widespread systemic gene expression was measured throughout the body, with cellular tropisms similar to those observed in the mouse studies and no observable adverse events.

The major drawbacks to the widespread use of gene expression profiling include reservations regarding their cost/effectiveness ratio and their lack of widespread availability.