Sentence examples for widespread function and from inspiring English sources

However due to widespread function and highly pleotropic nature, Notch inhibition raises the possibility of unanticipated adverse effects in host tissues including gastrointestinal toxicity after GSI treatment or formation of vascular tumors after DLL4 ligand blockade [ 4, 5].

These results identify a distinct, and potentially widespread function of dysbindin in promoting the sorting of specific GPCRs to lysosomes after endocytosis.

Here we show that dysbindin-dependent regulation of surface receptor expression is not restricted to neurons or to the D2 receptor, and identify an apparently widespread function of dysbindin in regulating GPCRs by promoting their sorting to lysosomes after endocytosis.

This widespread function compunction is neither outgrown nor fully replaced by formal scientific education.

Dark Inquiry's goal is to build compounding revenue generated from Bail Bloc to help The Bail Project secure the release of possibly thousands of low-income people from pre-trial incarceration, thereby diminishing the widespread function of cash bail to coerce guilty pleas.

Because of the widespread function of glycosylation, inherited disorders of glycosylation are multisystemic.

Increasing evidence suggests that SWI/SNF complexes have a widespread function in tumor suppression.

It has been proposed that restriction of ethylene production may be a widespread function of ABA.

The widespread function of miRNAs has been a target of several other studies in the pursuit of novel cancer treatments.

The interaction of calcium signaling with the cAMP-pathway via regulation of adenylyl cyclase [ 145] suggests a rather widespread function of calcium in regulation of cellular events.

Given the widespread function of Pin1 in mammalian cells, it seemed plausible that Ess1 in yeast may regulate pathways in addition to those involved with RNAPII.