Sentence examples for widespread function from inspiring English sources

In addition to a widespread function in maintaining neural progenitors, Notch signalling has also been involved in specific neuronal fate decisions.

These results identify a distinct, and potentially widespread function of dysbindin in promoting the sorting of specific GPCRs to lysosomes after endocytosis.

Here we show that dysbindin-dependent regulation of surface receptor expression is not restricted to neurons or to the D2 receptor, and identify an apparently widespread function of dysbindin in regulating GPCRs by promoting their sorting to lysosomes after endocytosis.

Furthermore, our results demonstrate that Math6 is indispensable for early embryonic development and indicate a more widespread function for this factor in tissue-specific differentiation processes that are dependent on class II bHLH genes.

Because of the widespread function of glycosylation, inherited disorders of glycosylation are multisystemic.

Increasing evidence suggests that SWI/SNF complexes have a widespread function in tumor suppression.

HDA1 has widespread functions in the yeast genome [52,63].

Most of these pathways have widespread functions in various tissues and at different stages.

The widespread functions of ZEB proteins in human malignancies indicate their significance.

Such widespread functions that occur independently of apparent sequence-specific DNA-binding proteins are referred to as 'global' histone modifications.

The widespread functions of Cdk5 in nervous system development have confounded efforts to understand the role of mammalian Cdk5 in neurodegeneration in vivo.