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While barely expressed under basal conditions, immunofluorescence demonstrated widespread expression in the nucleus of TH expressing chromaffin cells in the adrenal medulla after IMO stress [ 26].
Rescue experiments for D0067-Gal4 were not possible as the rescue strain dunce1; D0067-Gal4/UAS-dunce was larval-lethal, possibly due to widespread expression in the brain beyond the mushroom bodies (Figure 4B).
In agreement with our findings, previous reports showed that Igdcc3, which encodes a neural cell adhesion molecule, has widespread expression in the mesenchyme of the facial prominences at E10.5, but soon after becomes limited to discrete regions of the CNS [37], [38].
Both proteins showed widespread expression in the normal mouse retina.
In contrast, the P17L mutant DSP showed widespread expression in the cytoplasm.
CBX1A and DNMT3AA showed more widespread expression in the developing brain.
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The lack of an asymmetric distribution and the widespread expression in non cortical areas observed in the present study does not support PCDH11X/Y's role in human-specific faculties, but it is worth noting that the antibodies were broad in their specificity and individual isoforms may yet be found in a more restricted pattern in cortical areas related to language.
All these genes were expressed in the NSCs in an age-dependent manner (Fig. 6B): CBX7A was not detected in young animals and showed a widespread expression in old animals including both the postmitotic neurons and the stem cell niche.
Although integrase and RT domain showed similarly to retroelement A, and LINE widespread expression in both sexes and all tissues, the LTR B region was expressed only in the floral buds of both sexes.
An Rtnl1 exon trap insertion tagged with yellow fluorescent protein (YFP) (Fig. 1B) showed widespread expression in third-instar larvae, with the highest levels observed in neural tissues.
Like PrPC, ZIP6 and ZIP10 exhibit widespread expression in biological tissues with high transcript levels in the brain [19].
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