Sentence examples for widespread entry from inspiring English sources

A recent candidate with many of the properties required for widespread entry is an unknown molecular client of the ER (endoplasmic reticulum) chaperone gp96, but the mechanism by which this enables virus entry remains unclear [ 57, 58].

A recent study showed that incubation of cultured astrocytes in the nominal absence of extracellular bivalent cations (Ca2+ and Mg2+) opens channels (hemichannels or pannexin channels) that allow rapid, widespread entry of Lucifer Yellow into astrocytes (Ye et al., 2003); the presence of Mg2+ during the scrape-loading would prevent opening of these channels.

As with gp64, VSV G has been used to enable widespread vector entry of mammalian cells [ 53, 54] and the identity of the receptor or receptors required for entry has been similarly challenging [ 55, 56].

Nonetheless, the efforts of the three schools offering foundation programmes seem to have been far more successful in diversifying the future medical profession than the more widespread graduate entry initiative.

As the mechanism of widespread cell entry in the absence of a specific receptor would underpin the further development of AcMNPV as a generalized transducing virus and illuminate how entry occurs at the molecular level we have investigated the basis of entry into both adherent and suspension cells to define the entry requirements and the role of gp64 in it.

Not that widespread school-leaver entry into law is a new phenomenon.

The deal is receiving widespread approval from entry-level workers, who earn about half as much as longtime workers and would get raises of several dollars an hour if the contract passes.

In contrast, deletion of Rb is not sufficient to initiate liver cancer development but has been shown to cause widespread cell cycle-entry in hepatocytes [44].

However, purposeful addition of AcMNPV to mammalian cells in the culture has demonstrated that it is capable of widespread and efficient cell entry [ 5, 50] and that entry depends on the single virus surface glycoprotein gp64 [ 9]. gp64 is structurally very similar to VSV G, a bona fide arbovirus transmitted to large mammals by Simuliidae flies [ 51].

Third, the complexity of screening patients for this therapy will undoubtedly slow its entry into widespread use.

Although there are several AES within the UK, the most widespread is England's entry level stewardship (ELS), which covers ~62%% of English farmland (5.7 M Ha) as of January 2013 (Natural England 2013a).