Sentence examples for widespread editing from inspiring English sources

Systemic injection of high-titer particles led to gene expression in mouse liver and transferring Cre-recombinase mRNA in muscle permitted widespread editing at the ROSA26 locus.

Where Goldsmith believes that the creative processes brought on by new technologies, like word processing and programming, are reinventing writing, Hertz sees image manipulation algorithms, and widespread editing techniques, as shifting the parameters of imagery in the 21st Century.

These include the widespread editing of Alu-type repeat elements in the human transcriptome [5] [7] and the editing of micro RNA precursors [8] [10].

An inventory of RNA edit sites shows that widespread editing is not limited to coding regions in the tobacco mito-transcriptome.

Widespread RNA editing comes at a cost.

The most widespread genome editing technology in current use is the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein-9 nuclease (Cas9) system, which consists of Cas9 nuclease and a guide RNA (gRNA) that targets the genomic sequence of interest16, 17.

Therefore, it can be suggested that the widespread RNA editing in non-coding regions has a significant role in hESC early differentiation.

This locus contains the candidate gene Apobec1 which is known to alter circulating lipoprotein composition, but also has widespread RNA editing capabilities, perhaps indicating an additional mechanism by which susceptibility to atherosclerosis is regulated.

T. cruzi displays many unusual biological features: specialized intracellular compartments, such as the glycosome (in which the initial reactions of glycolysis occur) [ 16, 17], acidocalcisome [ 18], and reservesome [ 19]; widespread RNA editing of mitochondrial transcripts [ 20]; polycistronic transcription [ 21]; and trans-splicing [ 22], to name a few.

It is possible that decreased dADAR expression at 30°C is adaptive outside of the direct impact on widespread or specific editing.

Errors during amino acid recognition do not usually compromise the accuracy of translation due to highly specific aaRS enzymes, and the widespread existence of editing mechanisms that proofread non-cognate amino acids.