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The BAPQ may offer a comprehensive way to assess the widespread deleterious impact of adolescent chronic pain in both a research and clinical setting.
"Disabling of mitochondria could have widespread deleterious effects across systems, leading to greater susceptibility to infectious disease, an effect of this fungus already documented," she says.
Driven essentially by random genetic drift, subfunctionalization has been identified as a possible non-adaptive mechanism for the retention of duplicate genes in small-population species, where widespread deleterious mutations are likely to cause complementary loss of subfunctions across gene copies.
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It received great interest not only because of its widespread and deleterious nature, but also because of its unresolved etiology till date.
Beam trawling has widespread effects on the biomass, production and diversity of benthic communities and in some fisheries, the impact is deleterious.
However, analyses on sexual oDNA recombination in yeast and Chlamydomonas somewhat argue against the widespread occurrence of deleterious epistasis between oDNA alleles, since the expected segregation distortion is not normally observed (Box 4).
Because sulfides in the ores reduce cyanide extraction efficiency, workers may resort to ore roasting pretreatment, which would cause widespread contamination by deleterious sulfur dioxide gas and airborne roaster particulates with highly bioaccessible lead (Plumlee and Morman 2011).
However, fungal pathogens are the causal agents of economically more deleterious and widespread diseases in barley.
Hybridization with a more common, widespread invader is potentially deleterious and often seen as a threat for rare specialized endemics [ 4, 5].
More generally, developmental instability is associated with worse health outcomes, illness, and fetal stresses [27], which could be due to deleterious effects of widespread mutation and explain links of intelligence with mortality.
Although continued expression of ΦC31 has been shown to lead to chromosomal aberrations in primary human fibroblasts [15], R26ΦC31 and R26ΦC31o heterozygous or homozygous mice were viable and neither showed any obvious deleterious effects from the widespread expression of the SSR.
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