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Protein-based serum biomarkers have been assessed in relation to diagnosis and patients' stratification, but general lack of robustness and reproducibility impede widespread clinical utilization.
Ex vivo gene therapy using lentiviral vectors (LVs) is a proven approach to treat and potentially cure many hematologic disorders and malignancies but remains stymied by cumbersome, cost-prohibitive, and scale-limited production processes that cannot meet the demands of current clinical protocols for widespread clinical utilization.
This approach, namely Individualized Mutation-weighed Phenotype On-line Search I-MPOSS), aims to address the above mentioned issues and facilitate widespread clinical utilization of ES.
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In contrast, no method for assessing tissue oxygenation has yet gained widespread clinical use.
Despite considerable research efforts, no novel biomarkers of AKI are currently in widespread clinical use.
At least two major hurdles need to be addressed to stimulate widespread clinical use.
There is no single method of assessment that is in widespread clinical use.
GnRH analogues have achieved widespread clinical use for the control of reproduction in animals.
However, despite their widespread clinical use, these techniques have a number of potential limitations.
Finally, the major hurdles on the way to widespread clinical use are reviewed.
Implantable intracortical microelectrodes face an uphill struggle for widespread clinical use.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com