Following World War II and the work of his research team in North Africa, penicillin came into widespread clinical use.
"There is so much hope invested in stem cells that it's sobering for all of us to realize what a long time it takes to bring a safe and effective therapeutic into widespread clinical use," Dr. Hall said.
Despite considerable research efforts, no novel biomarkers of AKI are currently in widespread clinical use.
In contrast, no method for assessing tissue oxygenation has yet gained widespread clinical use.
At least two major hurdles need to be addressed to stimulate widespread clinical use.
There is no single method of assessment that is in widespread clinical use.
However, despite their widespread clinical use, these techniques have a number of potential limitations.
Finally, the major hurdles on the way to widespread clinical use are reviewed.
Implantable intracortical microelectrodes face an uphill struggle for widespread clinical use.
Despite the widespread clinical use of pedicle screw fixation, there is relatively little literature concerning accuracy.
Various selective COX-2 inhibitors were in widespread clinical use from when they first gained FDA approval in 2000.
