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Challenging widespread clinical practice and accepted treatment guidelines, Dr. Holly Prigerson, Irving Sherwood Wright Professor in Geriatrics, has published a paper in JAMA Oncology that puts the value of chemotherapy for end-of-life patients with cancer into question.
On-going large prospective multi-center clinical trials will provide us with information regarding the clinical utility of two of these assays, but for now, implementation of these models into widespread clinical practice remains limited.
While clonogenic assays soon fell out of favour due to their high failure rate, other cellular assays fared better and although they have not entered widespread clinical practice, they have proved to be very useful research tools.
The PMC provides a structure for achieving consensus positions among these stakeholders on crucial public policy issues, a role which will be vital to translating personalized medicine into widespread clinical practice.
This reflects the widespread clinical practice of observing patients following epinephrine, rather than immediately discharging them.
The off-label use of medicines is a common and widespread clinical practice worldwide [ 2, 3].
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This new consensus statement was, therefore, drawn up to provide a comprehensive series of practical and easily applicable advices to further widespread good clinical practice in the field.
The measurement of arterial pressure, both in the clinic and on an ambulatory basis, is very widespread in clinical practice, and its direct correlation to mortality and morbidity has been extensively studied [ 44- 46].
Endectocide compounds are extensively used for broad-spectrum parasite control and their topical administration to cattle is widespread in clinical practice.
Only 10 Japanese CNC cases, including our case, have received the PRKAR1A genetic test, and most of them were recent, between 2013 and 2017, indicating that the genetic test has not been widespread in clinical practice.
Despite ongoing disagreement as to the role of antidepressants in the treatment of bipolar disorder (Altshuler et al. 2003; Ghaemi et al. 2008; Möller and Grunze 2000; Pacchiarotti et al. 2013), long-term prescribing of antidepressants remains widespread in clinical practice.
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