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Biologically, Vav1 plays a critical role in hematologic cell signaling, whereas Vav2/3 have a wider tissue distribution, but all 3 Vav proteins are implicated in cancer development.
Bnc2, a closely related homolog of Bnc1, has a much wider tissue distribution than that of Bnc1 [42], [42]; and both are reportedly co-present in keratinocytes and oocytes [26], [41] [43].
However, it is now know that TRPM8 has a wider tissue distribution and is present in non-neuronal cells and tissues that usually do not experience low temperatures such as gut [16], vascular smooth muscle [17], liver [18] and lung [19], therefore its role is far from being understood.
Fracture contaminates the surrounding tissue bed with tumour, and resection will necessitate wider tissue margins.
In adults, human NAT1 has a much wider tissue distribution than human NAT2.
In brief, B7x also seems to have a much wider tissue distribution than the original B7-1 and B7-2 moleculesimilarlar to that of B7-H3.
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This finding would be consistent with the much wider tissue-distribution of the Dad1 gene normally found on the LCR's 3'-flank in the genome.
Similar compound, Cu-diacetyl-bis(N ethylthiosemicarbazone) (Cu-ATSE), has wider tissue-oxygenation level specificity than Cu-ATSM.
Cyclic nucleotide phosphodiesterases (PDEs) are a diverse enzyme group with multiple regulatory properties and wide tissue distribution.
Moreover, targeted mutations in MLN64 (Stanotheranother START member with wide tissue distribution, impair steroidogenesis while causing minor alteration in cholesterol metabolism [93].
The method of grid crossings proposed here can instead be applied to big image data sets, allowing to obtain measures over wide tissue portions in a limited time.
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CEO of Professional Science Editing for Scientists @ prosciediting.com