The active enzyme exhibited wide substrate specificity and marked thermal unstability.
Microbial peroxidases have wide substrate specificity and can easily interact with hydroxyl and methoxy-substituted phenols (Kim and Shoda 1999; Yang et al. 2005).
All these results confirm that TolC of L. pneumophila Lens is a component part of a functional efflux pump with wide substrate specificity and driven by the proton motive force.
The transporters have wide substrate specificity, and this binding to many compounds can result in inhibition of activity by competing substrates.
This enzyme can be exploited for a wide-ranged application in various industries owing to its stability, wide substrate specificity, and fibrinolytic and gelatinolytic properties.
MMP-1 has a wide substrate specificity and is capable of degrading aggrecan, versican, perlecan, nidogen, serpins and tenascin-C (McCawley and Matrisian 2001).
After immobilization in calcium alginate gel protocatechuate 3,4-dioxygenase showed wide substrate specificity and the iron was strongly bind at the active site.
The substrate-binding pocket of R. perezi ADH1B is extremely hydrophobic and space-restricted, resulting in low Km values for aliphatic alcohols, it has wide substrate specificity and is moderately active with retinoids [ 18].
2 Evidence is increasing that ECHS1 has a wide substrate specificity and thus also plays an important role in amino acid catabolism, in particular of valine, where it converts methacrylyl-CoA to (S -3-hydroxyisobutyryl-CoA and acryloyl-CoA to 3-hydroxypropionyl-CoA (Fig. 1), the fourth S -3-hydroxyisobutyryl-CoA
The third protease implicated in the metabolism of gastrin is NEP, an ectoenzyme with broad substrate specificity and a wide distribution in the body.
