Sentence examples for wider specificity from inspiring English sources

Selections with labeled FQs resulted in several mutant antibodies with increased affinity or wider specificity toward different FQs.

The fusion proteins bound human and mouse IgGs and their fragments with up to 58-times higher affinity and wider specificity than the parental binding domains.

The abundance of the drug transporters and their wider specificity suggest that they may not be exclusively drug exporters in microbes and may have other cellular functions.

These observations and the extreme plasticity of the ALR cluster in mammals (Brunette et al. 2012) indicate that diversification at ALR genes is evolutionary advantageous and possibly confers wider specificity in foreign nucleic acid recognition.

Europium III) chelate has recently been advanced as an NO fluorescent probe but its wider specificities are yet to be fully assessed (Chen et al. 2011).

Mammalian nucleotide excision repair (NER) eliminates the broadest diversity of bulky lesions from DNA with wide specificity.

Indeed, additional genome-wide specificity assays are sorely needed for in-depth and accurate investigation of the in vivo specificity of base editors.

This is because it often relies on generic or representative reactions to show the reactions catalysed by enzymes of wide specificity.

Although we did not find off-target effects at the top 10 potential off-target sites examined, the specificity of base editors needs more comprehensive investigation through genome-wide specificity assays, such as Digenome-seq (Kim et al., 2017a).

X-ray crystallographic analysis and molecular modeling experiments explained the wide specificity of QF34: this inhibitor binds to the PR in an unusual manner, thus avoiding contact sites that are mutated upon resistance development, and the unusual binding mode and consequently the binding energy is therefore preserved in the complex with a resistant variant.

The fact that inhibition of AP activity is only induced by some IxACs in only one bird and one reptile might seem surprising given the very wide specificity of I. ricinus.