Sentence examples for wider range of binding from inspiring English sources

Previous structural modelling of AbrB bound to the target DNA sequence indicated that the AbrB tetramer would interact with ∼20 bp sequences, whereas in vitro footprinting studies detected a wider range of binding regions from 25to8080 bp.

Structural modelling of AbrB bound to the target sequence indicated that the AbrB tetramer would interact with ∼20 bp sequences, whereas in vitro footprinting studies detected a wider range of binding regions from 25 to 80 bp, suggesting that a higher order structure of the AbrB tetramer may be involved in DNA binding at some sites on the chromosome.

Natural evolution has resulted in protein molecules displaying a wide range of binding properties that include extremes of affinity and specificity.

The mAb capture density of less than 0.6 nm was found to be optimal to measure a wide range of binding affinities on Octet HTX biosensor.

Our integrated analyses reveal that half of the marketed drugs and most of the drugs in clinical trials that interact with peptide GPCRs are small molecules with a wide range of binding modes distinct from those of large peptide ligands.

In general, when combined with the high-energy barrier of the transition state, extra energy input into the signaling process would increase the signal-to-noise ratio and thus permit faithful yet low-noise responses to a variety of ligands of a wide range of binding affinities.

As an example, DR-1 peptide (26 amino acids) spanning cyclin D1-a amino acids 42 67, is predicted to generate multiple overlapping 15 amino acid epitopes that have a wide range of binding efficiency to HLA-DR.B1-0101, -0301, -0401, -0701105105 & 1501.

The cooperative binding of multiple RBDs that recognize similar sequences allows realizing a wide range of binding specificities and affinities to different mRNAs.

However, these direct binding proteins are targeted by EGCG at a wide range of binding affinities [ 35]; thus, the cellular functions targeted by EGCG are largely dependent on the doses used in the experiments.

We found a wide range of binding of [3H]misonidazole to cells adjacent to the necrotic core, analogous to the patterns seen in xenografts, indicating substantial differences in the central oxygen tension of the spheroids.

Thus, the applied model is a powerful tool for describing photoconduction in NC devices, which are often governed by carrier trapping into states with a wide range of binding energies.