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An estimated GFR decline of 40% may be more broadly acceptable than a 30% decline across a wider range of baseline GFRs and patterns of treatment effects on GFR.
This reflects the reality in daily clinical practice and allows results to represent patients with a wider range of baseline levels of GH secretion and a broad range in GH responsiveness.
For a higher disease risk, rare variants with strong effects showed improvement in AUC across a wider range of baseline AUC values and significant positive NRI >0.01) and IDI.
Only when the OR of the rare variant was very large, its frequency higher and disease risk high, were the AUC and NRI >0.01) improved across a wider range of baseline AUC.
Similar(56)
Consequently, a wide range of baseline data is required in order to provide comparisons in the case of emergent themes.
As physical activity behaviour is influenced by a variety of factors from multiple domains [ 19], we included a wide range of baseline predictors.
This was a prospective study including a wide range of baseline measurements and an open-label treatment phase in a subgroup of cough patients.
However, this patient cohort had a wide range of baseline cardiac reserve, as manifested by having only 30 of 50 patients being volume responsive.
The data also show that cortical cells exhibiting a wide range of baseline firing rate were inhibited, emphasizing the robustness of central thalamus-driven cortical inhibition.
In terms of husbands' smoking, a wide range of baseline smoking prevalence by stratified categories might result in unstable DID estimates with limited significance.
The average CD4 counts for patients with multiple versus single strain infection were similar, and patients with multiple strains had a wide range of baseline CD4 counts.
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