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Organizing around micro-enterprises promotes the benefits of cohesiveness, motivation, commitment, productivity, and "a wider interaction between the organization and its environment" (Leavitt, 1975:17; Meyer, 2017).
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Our study identifies a genome-wide interaction between the prolongevity transcription factor FOXO3 and the cell-fate determinant ASCL1 and raises the possibility that FOXO3's ability to restrain ASCL1-dependent neurogenesis may help preserve the neural stem cell pool.
The current RIP-seq approach has been developed for the identification of genome-wide interaction between RNA binding protein (RBP) and the bound RNA transcripts, but still rarely for identifying its binding sites.
Our results suggest pervasive, genome-wide interaction between co-expression domains.
The technique allows a wider interaction region between the probe and the pump beams, then the experimental setup sensitivity improves highly.
With the development of HTS RNAi screens, it became possible to examine genome-wide interactions between viruses and host factors.
Here we employ in vivo cross-linking to identify transcriptome-wide interactions between piRNAs and target RNAs.
For example, the genome-wide interactions between miRNAs and the pluripotent core factors (Nanog, Pouf1 and Sox2) could be extracted from this network (Fig. 1d).
Here, we have developed a computational method to dissect the genome-wide interactions between ATP-dependent chromatin remodeling and the covalent modification of histones.
We developed the Weighted Interaction SNP Hub (WISH) network method that uses HTG data to detect genome-wide interactions between single nucleotide polymorphism (SNPs) and its relationship with complex traits.
To better understand the genome-wide interactions between Tip60 and c-Myc at the chromatin, we analysed the overlap between Tip60 and c-Myc high-confidence binding sites, which were identified by MACS14 peak calling algorithm [ 21].
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