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I've got a much wider hypothesis about what consumers make of this situation,which is a bit tangential to your questions... PHR: We expect Apple to come to the market with a more convincing TV games-related proposition in the future.
Using a grounded theory approach [ 36], from this initial analysis, a wider hypothesis was generated to interpret the findings.
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The position-dependent local parameters, which make the model heterogeneous, allow the model to interpolate between a homogeneous sequence-wide hypothesis and one that ignores correlations.
We intend to use a genome-wide hypothesis-generating approach, sequencing the 'whole exome' and 'whole genome' of children with TB enrolled in this study [38] [40].
Massively parallel sequencing allows for genome-wide hypothesis-free investigation of for instance transcription factor binding sites or histone modifications.
Hundreds of thousands of SNPs can be typed using these platforms, yielding a genome-wide, hypothesis-free scan of genetic associations for a given phenotype of interest.
Conclusive evidence would still require a standard definition of AKI, unbiased outcome measures and replication of associations in a large independent sample and, preferably, applying a genome-wide hypothesis-free study design in future research.
Since the regions used are unlinked, we favour a population demographic expansion against a genome wide selection hypothesis in S. fimbriatum.
WGS remains expensive though, so it may be some time before WGS studies reach the sample sizes necessary to discover genetic influences on highly polygenic diseases at the significance thresholds required, given genome-wide multiple hypothesis testing.
However, their data contradicted the wide-hybridization hypothesis; instead these authors suggested that the founding hybridization involved two closely related species ancestral to the genus Gillenia (x = 9), followed by loss of one pair of chromosomes [ 24].
Several common CNVs have been reported to be associated with complex diseases (reviewed in [37]), however, these CNVs were identified by candidate gene approaches instead of genome-wide and hypothesis-free surveys [37].
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CEO of Professional Science Editing for Scientists @ prosciediting.com