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But any subsequent policy action must be supported by a wider evidence base – policymakers should not rely upon Pisa alone.
Finally, the data and outcomes can be incorporated as part of a wider evidence base that might lead to future research outputs.
Reflecting the wider evidence base, the campaign strategy sought to influence both individual and environmental factors.
Efforts to support knowledge translation in LMICs need to both take account of these factors and incorporate evaluation, so that a wider evidence base for knowledge translation in these settings can be developed.
Further consideration should be given to clinical practice patterns of other causes of LBP and musculoskeletal disorders and common empirical treatment methods to the aim of constructing CPGs supported by a stronger and wider evidence base.
28 29 Our results also reflect a wider evidence base indicating that improvement initiatives may often have limited or no demonstrable effect on quality, and that this may often be associated with contextual factors.
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Cholinesterase inhibitors are effective for cognitive and neuropsychiatric symptoms; rivastigmine has the widest evidence base.
There are no head-to-head trials comparing efficacy of the cholinesterase inhibitors in DLB or PDD, but rivastigmine has the widest evidence base [ 12, 18, 19].
Positive influences or 'drivers' for CAM policy formation were identified as: existing services, local enthusiasm and expertise, patient demand, a willingness to consider the wider evidence-base for CAM, and a perception that complementary therapies could help the PCOs to meet national NHS targets.
Our experiences and the wider evidence-base suggest that a potential way forward may involve implementing a combination of standardised core solutions and customised elements, corresponding to particular users and environments (also known as 'configurational technology') [ 72, 73].
However, despite wide use, the evidence base to support QICs is surprisingly modest. 1 In this issue of the journal, Knight et al 2 provide useful information suggesting that QICs in Australia had a positive impact on diabetes care.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com