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A widened role for β-arrestin includes control of two new signaling elements in addition to the G protein-coupled receptors.
This widened role of PPAR gamma will certainly initiate a new flurry of research, which will not only refine our current (and often partial) knowledge of PPARgamma, but more importantly, will also establish that this receptor has a definite role as a primary link adapting cellular, tissue and whole body homeostasis to energy stores.
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The number of lawyers per thousand population nearly tripled between 1970 and 1998, largely in response to the widening role of governments and a boom in litigation.
Data Monitoring Committees (DMCs) often undertake such analyses, but their widening role may lead to extended use of interim analysis or recommendations that could potentially bias trial results.
The Heat, starring Bullock and Melissa McCarthy, was another film that prompted buzz over supposedly widening roles for female actors.
Decades later, despite the widening roles for women in combat and throughout the services, the military continues to struggle with persistent reports of violence, rape and mistreatment of women in the ranks.
The White House then announced it had widened its role in the Gulf ordering American warships to aid any neutral vessels under attack.
Rather, it seems to recognize the widening role cellphones play in society.
"U.S. Widens Role in Battle Against Mexican Drug Cartels" (front page, Aug. 7) states that "the new efforts have been devised to get around Mexican laws that prohibit foreign military and police from operating on its soil".
Since first identification of the first UBLp (the interferon stimulated gene 15, ISG15) in 1979 additional UBLps (at least 10 to date) have been described with an escalating frequency and evidence of UBLps ever-widening role in the modification of cellular processes [17], [23].
But if Shenhua turned out to be commercial mistake, how could an old striker widen his role in life?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com