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However it remains uncertain whether these two TE families invaded the fungal genomes before the Capnodiales- Pleosporales separation and then were widely lost in the Capnodiales or if their presence only in P. fijiensis is incongruent with vertical inheritance.
The genes encoding hydrogenosomal enzymes are either ancestral to all eukaryotes and have been widely lost in aerobic lineages or they have been circulated among anaerobic eukaryotes by multiple events of lateral gene transfer [5].
Although RabX4 is present in insects and not in vertebrates, it is also present in a few genomes of more primitive metazoans (for example, Amphimedon queenslandica, Nematostella vectensis and Strongylocentrotus purpuratus), indicating that it arose early in metazoan evolution and was widely lost.
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