RAGE is widely localized in many cell types such as smooth muscle cells, hepatocytes, neurons, endothelial cells, and monocytes.
Because motor neurons are widely localized in the cranial motor nerve nuclei in the brainstem and the anterior horns of the entire spinal cord, systemic injection of a vector is preferable to local injection to provide global gene delivery to the motor neurons of ALS patients.
We also found that marker of mesoderm cells (cardiac protein, widely localized in cardiac muscle cells) was expressed in the EB-like structures and the expression of integrin α6, a marker of pluripotent stem cells, was remained after in vitro differentiation).
Localization of magnetoencephalographic rhythms generated in this fashion reveals widely distributed, localized sources of flicker-entrained neural activity in the cortex [39].
For example, it occurs widely, though localized, in Aragón, where Myotis sp. A (the only other species in the M. nattereri complex to occur there) is known from a single locality only.
In the trunk it is widely present, localized in the lymphatic vessels and 8(b)), including the ISLV and PCLVs, where it presents the same distribution of CDF/LIF, white arrow) and in sites where it exerts its neuromuscular function, associated to the muscle, miocommas, and ventral neurons of the neural tube, 9(d), and 9 e), arrows).
There has never been a Disney musical so widely translated (or "localized," in industry-speak) as "Frozen".
In the fetal rat hypothalamus, T/EBP/NKX2.1 was localized widely in the ventral hypothalamic areas.
Different curricula such as the Project Approach, Reggio Emilia and Montessori have been widely adopted and localized (Li. H. & Li, P., 2003).
However, because motor neurons are localized widely in the nuclei of cranial motor nerves and the spinal cord, global delivery of therapeutic agents to the motor neurons is required to accomplish therapeutic effects.
It is now widely accepted that localized platelet and fibrin thrombosis at the site of infection is a physiologic reaction that protects against dissemination of microorganisms and pathogen-associated molecular patterns derived from them into the systemic circulation, which is now called immunothrombosis [ 5].
