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Proteins in biological systems seldom work as independent entities, rather they are placed in widely interacting regulatory networks.
Being driven by coverage, the algorithm is inherently biased towards clusters of "widely interacting" trans-factors.
In addition, p38 mitogen-activated protein kinases (MAPKs) were clearly delineated by identification of their widely interacting partners by AP-MS [ 51].
An additional alternative workflow supported by PTR combiner regards the mining step of the algorithm and arises from the previously discussed bias of the algorithm towards "widely interacting" trans-factors (see Mining combinatorial features).
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In addition, colloidal or particulate carrier systems widely interact with cell microenvironment and are widely used as cargo carriers in vaccine therapies of CNS pathogens (Table 3).
Traveling widely, and interacting with the highest military commands and royal families, McClellan observed the siege of Sevastopol.
It has been widely observed that epistatically interacting gene pairs are more likely to share annotated biological properties than randomly selected gene pairs [ 24].
Increasingly, I think we'll see people use the Watch as a device that can interact widely with its surroundings, and this is a good initial example of that kind of thing.
Warfarin, a widely used anticoagulant, interacts with various agents used in palliative care, such as oxycodone, morphine, acetaminophen, and non-steroidal anti-inflammatory drugs (NSAIDs) [1]; thus, an interaction with a concomitant medication is crucially important.
Warfarin, a widely used anticoagulant, interacts with various agents used in palliative care, such as oxycodone, morphine, acetaminophen, and non-steroidal anti-inflammatory drugs (NSAIDs); however, there are no reports of its interaction with methadone.
Protein secretion systems are widely used to interact with abiotic environments, host eukaryotic organisms, and other bacteria.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com