Acamprosate is a widely utilized, efficacious treatment for relapse prevention in alcohol dependent patients.
MSCs have been considered safe as they do not show tumor formation after transplantation and have been widely proven efficacious in preclinical and clinical studies for cardiovascular and neurodegenerative diseases, graft-versus-host disease and autoimmune disease.
"If bacterial therapy is going to be widely available and efficacious," Hoffman says, "it has to target metastatic disease".
Biodegradable polymeric nanoparticles are widely recognized as efficacious drug delivery vehicles, yet the rational engineering of nanoparticle surfaces in order to improve biodistribution, reduce clearance, and/or improve targeting remains a significant challenge.
Lithium is one of the most widely used and most efficacious drugs in the different treatment phases of bipolar disorders (Severus et al. 2012).
Oral non-steroidal anti-inflammatory drugs (NSAIDs), the most efficacious and widely used treatments for knee OA, have shown some risks of systemic adverse events including gastrointestinal or cardiovascular abnormalities [7].
Dipeptidyl peptidase-4 (DPP-4) inhibitors are now a widely used, safe and efficacious class of antidiabetic drugs, which were developed prospectively using a rational drug design approach based on a thorough understanding of the endocrinology and degradation of glucagon-like peptide-1 (GLP-1).
Various options are available, with the most efficacious and widely used being talc pleurodesis.
Indeed, SLIT has become a standard treatment for aeroallergen-induced ARC and is widely acknowledged to be efficacious, safe, and well tolerated [ 1, 6, 7].
No previous studies have undertaken a meta-analysis with NSAIDs, which is one of the most efficacious and widely used treatments for knee OA [ 5].
