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We identified an apparent over reliance on the arbitrary but widely used cut off of 0.05 to distinguish between significant and non-significant results.
There are no normal population values for the HAD scale, but there are widely accepted cut off values which have been validated in several studies [ 11].
This might open a clinical perspective for this marker also in the context of CTC measurements because even in metastatic breast cancer a relevant portion has CTC counts below the widely established cut off of five or more CTC in 7.5 mL blood.
At this point, I'd like to say a big fat "fuck you" to the fashion industry for apparently having decided that all high-street chains should only sell high-neck, widely-cut clothing that makes big breasted women look like overweight pyramids.
Opec members are widely expected to cut production, after the oil price tumbled this autumn.
The Fed is widely expected to cut rates again at its meeting next week.
The Bank of England is widely expected to cut rates at its February meeting.
The Fed is widely expected to cut rates again at next week's meeting; many analysts expect a half-point cut.
Investors are also looking ahead to Tuesday, when a Federal Reserve committee is widely expected to cut interest rates.
It is widely expected to cut interest rates further and/or lower reserve requirement ratios for all banks this year.
It is widely expected to cut base rates again, to 0.1%, before the end of the year.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com