Due to their complexity and wide-ranging utility, biomacromolecular research is an especially interdisciplinary branch of chemistry.
As summarized in Table 1, these studies showcase the wide-ranging utility of miRNAs as markers of disease, in terms of diagnosis, prognosis, disease subtype classification, treatment monitoring, and agents of intervention.
Despite their wide-ranging utility, ESTs have two inherent drawbacks: (1) they are based on single sequence reads making them vulnerable to sequencing errors, and (2) they are generated from cDNA libraries that may contain unexpressed or incompletely spliced sequences derived from heteronuclear RNA or other artifacts.
Senators Ron Wyden (Democrat, Oregon) and Mark Udall (Democrat, Colorado), the chief inquisitors of US intelligence officials during the current surveillance scandal, added a sharp warning late Tuesday that senior intelligence officials "are not always accurate" in their public statements about the scope and utility of their wide-ranging surveillance efforts.
The current study demonstrates the utility of using wide-ranging fossil mammals to explore latitudinal gradients and patterns of C3/C4 grass distribution and continental palaeotemperature during the Pleistocene.
As part of a wide-ranging program to evaluate the clinical utility of WGS (WGS500), we sequenced six patients with severe early-onset epilepsy who had evaded molecular diagnosis by conventional single-gene clinical screening.
Common garden experiments are used to isolate the genetic contribution to overall trait change, but such experiments are difficult to perform in wild populations of wide-ranging, large-bodied species, limiting their utility for many species of interest.
Now Dr. Runge's agency is reviewing several safety issues involving sport utility vehicles that could have wide-ranging implications for motorists and automakers.
Although serologic analysis of wildebeest detected these differences, seroprevalence in wildebeest was lower overall, and the wide-ranging migratory movements of the Serengeti herds limit the utility of these data for detecting spatial patterns.
