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Given that pathways are essentially connected in vivo and that highly comprehensive experimental data that encompass a wide variety of pathways is readily available, arbitrary partitioning of pathways is often not useful for the mapping and observation of comprehensive experimental data.
The antibodies were selected from a wide variety of pathways, including apoptotic and cell signalling pathways.
To sum up, our phylogenomic data indicate a wide variety of pathways in different eukaryotic organisms.
Our screening identified a wide variety of pathways whose inhibition had potentially anti-metastatic effects (supplementary material Table S1).
Overall, the distribution of PARPs among eukaryotes indicates the importance of poly(ADPribosyl)ation in ancestor of all eukaryotes and their involvement in wide variety of pathways.
mTOR is a nutrient-regulated kinase that controls a wide variety of pathways involved in metabolism and cell growth (Wullschleger et al, 2006).
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A wide variety of pathway analysis tools exist today, some manually curated, and some created primarily through machine learning.
Although reduced vessel contractility may reflect a loss in responsiveness of a wide variety of contractile pathways, the PLC signaling pathway contributes significantly to this process.
A mathematical model was constructed based on the metabolic reaction network including 351 metabolites and 441 fluxes, which cover a wide variety of metabolic pathways related to amino acid biosynthesis, glycolysis pathway, TCA cycle, pentose phosphate pathway, GSL biosynthesis, and purine and pyrimidine biosynthesis.
As these kinases are upstream of a wide variety of other pathways that are involved in cell survival and proliferation, derangements of these pathways are often implicated in the development of a variety of cancer types.
The carbonyl group has a wide variety of reaction pathways open to it.
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